Ahh the problems of health affects on humans when you can't use them as test equipment. Killing rats in a lab with chemical doses does not scale up into the human race. The truth is 90+ % of the chemicals we use everyday were developed over the last 50 years or so. No one knows the long term affect of any of this. Take tooth paste for example. We all use it, or should. How much do you ingest on a daily basis? Certainly more than any BPA or plasticizer in a plastic bottle. How much of that tooth paste contains sodium fluoride or another fluoride? Most of it. Sodium fluoride is rat poison. Other fluorides are toxic as well. And we deal with it. There was a great book called the "Dose makes the poison". I forget the author. Anything is potentially toxic if you consume enough. Would you or could you consume it is the question.
At the end of the day the average human life span is increasing as is the quality of life. It can't be all bad.