I won't be trying to reprofile any edges. Mainly just small touch-ups and keeping a nice edge. I've heard there are some disadvantages to the sharpmaker because of the fixed angles, 30 and 40 degrees, do you guys ever have trouble with that?
You pretty much said it all right there. Because of the fixed angles, you may have no choice but to re-profile your edge.
My experience with Busse/SR/SY is that from knife to knife the grind angle is inconsistent. On one you maybe able to throw it on the sharpmaker and immediately put a bevel on it. On the next one, it might have a thicker edge, and require a lot of material removal.
As diceman already mentioned, the sharpmaker is not good for material removal mainly because the stones are not coarse enough. You will literally spend HOURS removing metal if the edge is not set up right.
All that stuff said, I think the sharpmaker is great. You just have to be aware of its limitations, and know when to use something different.