Easy: G19. Its the only one I own anyways. Knifewise I would guess the Trap will make my choice. This combination is what I usually carry when taking a gun into town. Its civil and carries enough punch to get me out of trouble. A fixed blade I don't think is required, there is enough stuff available in a city if you need a crowbar, so a knife should be used for cutting only therefore my choice for a folder.

My wife is probably buying a G26, I recommended it because of size and weight. Whats the point of a big handgun if it is uncomfortable to carry. Odds are you are not going to have with you when in need. The G19 or the G26 are both compact and reasonably light. And if you really want lots of firepower then combine them with a 31 mag (looks kinda silly though).

My approach to shooting: compensate accuracy by using stacked mags.