Some interesting stats:

Alcohol:
National Council on Alcoholism and Drug Dependence, Inc. (NCADD)
-Harmful use of alcohol results in the death of 2.5 million people annually

-320 000 young people aged 15-29 years die annually, from alcohol-related causes, resulting in 9% of all deaths in that age group.

Centers for Disease Control and Prevention (CDC)
-Alcohol abuse kills some 75,000 Americans each year
-34,833 people in 2001 died from cirrhosis of the liver, cancer and other diseases linked to drinking too much beer, wine and spirits.


Cigarettes:
CDC
- Worldwide, tobacco use causes more than 5 million deaths per year
- In the United States, tobacco use is responsible for about one in five deaths annually (i.e., about 443,000 deaths per year)

American Cancer Society
- Deaths from lung cancer: 160,340 (Males: 87,750/Females: 72,590)


Automobiles:

CDC
- Motor vehicle traffic deaths: Number of deaths - 34,485


National Highway Traffic Safety Administration's (NHTSA)

-Number of traffic fatalities in 2010: 32,788


Poisoning:

CDC
-In the United States, 31,755 people per year die as a result of unintentional poisoning


Firearms:
CDC
-Firearm Homicides 11,493

-Underlying Cause of Death 1999-2009

Other interesting facts:
Cause of Death/Number of deaths
Alzheimer's disease/77047
Parkinson's disease/20391
Cardiac arrest/13748