What MB said for the most part. I pretty much carry a handgun in an SLS holster no matter the type of carry, belt, concealment (though I have a Safailand 702 open top triggerguard jack holster) and thigh. Though there are certainly better concealment holsters about, keeping some consistency in release/draw is a huge advantage when you have to work by instinct, it is also very helpful in keeping a few spare parts available.
MB hits the nail on the head about walking long distances with a thigh rig on, it sucks (more so if you are made to RUN to the range and back a few times to warm up <img src="/ubbthreads/images/graemlins/wink.gif" alt="" /> ). IF speed of draw/retention is not your biggest concern some of the cordura thigh rigs will be more comfortable. I have an Eagle made jobby that dates back to the 80s that is still goping strong and is not too bad on the leg. if you use the secondary retention on it, it is not so quick to draw, if you don't use this it is very fast but I would not want to rely upon it to always retain my sidearm in a run/fall/trip/stumble/crawl/dig a hole to hide in with my eyelids situation.. <img src="/ubbthreads/images/graemlins/ooo.gif" alt="" />
If I were you I would borrow one and go walk up and down some hills with it for a couple of hours before you outlay the $$s. My first recommendation would still be a Safariland 6004 or 6005 (the 6004 is now out of production I think but can be picked up new or little used from e-whore at reasonable prices).
Andy