Our, Marines, martial arts program is a mix of Jiu Jitsu, kick boxing, boxing and many more disciplines. One of the elements introduced in the green belt curriculum is multiple opponents. Taking on two or more men is difficult to say the least.
You have to use angles to try and take one on at a time and keep your head on a swivel avoiding tunnel vision. That said, it usually comes down to "kill this guy before his buddy stabs me in the back so my comrades have less to fight when they get here."
