Not much out here that "needs" the .375, Asiatic Buffalo, Bantang and Scrub Bulls are about it. I have hunted buff with my .300Win but it was not the most comfortable feeling doing so. The .375 is also a great Sambar rifle but the .300 works well too. There is something truly SPECTACULAR about busting hogs with the .375 !!!!!!!! That said earlier in the year I was hunting bunnies with it as well (I work on the theory if I am confident snap shooting rabbits as I was through the bush I should be able to hit a Cape Buffalo OK).