I've recently become a true believer in the 450 Bushmaster. Built one and the oldest took a deer cleanly with it at about 125. A 250gr Hornady FTX has the same energy as a moderate modern 45-70 cartridge loaded with a 300gr bullet. Still has enough energy at 400 yards to take down elk-sized game (yes, it's quite the rainbow past 300-350 yards). I thought I was in love with the 458 SOCOM but this is crazy power out of a disproportionately tiny-size cartridge.